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Burkholderia cepacia complex : ウィキペディア英語版 | Burkholderia cepacia complex
''Burkholderia cepacia'' complex (BCC), or simply ''Burkholderia cepacia'' is a group of catalase-producing, lactose-nonfermenting, Gram-negative bacteria composed of at least 18 different species, including ''B. cepacia'', ''B. multivorans'', ''B. cenocepacia'', ''B. vietnamiensis'', ''B. stabilis'', ''B. ambifaria'', ''B. dolosa'', ''B. anthina'', ''B. pyrrocinia'' and '' B. ubonensis''. ''B. cepacia'' is an important human pathogen that most often causes pneumonia in immunocompromised individuals with underlying lung disease (such as cystic fibrosis or chronic granulomatous disease). Patients with sickle-cell haemoglobinopathies are also at risk. The species also attacks young onion and tobacco plants, as well as displaying a remarkable ability to digest oil. ==Pathogenesis== BCC organisms are typically found in water and soil and can survive for prolonged periods in moist environments. They show a relatively poor virulence. Virulence factors include adherence to plastic surfaces (including those of medical devices) and production of several enzymes such as elastase and gelatinase. Also relevant might be the ability to survive to non-oxidative killing by neutrophils.〔Torok E et al. Oxford Handbook of Infect. Dis and Microbiol, 2009〕 Person-to-person spread has been documented; as a result, many hospitals, clinics, and camps have enacted strict isolation precautions for those infected with BCC. Infected individuals are often treated in a separate area from uninfected patients to limit spread, since BCC infection can lead to a rapid decline in lung function and result in death.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Burkholderia cepacia complex」の詳細全文を読む
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